What is Revlimid?
Revlimid is a medication used to treat types of multiple myeloma, mantle cell lymphoma, follicular lymphoma, marginal zone lymphoma, and anemia in myelodysplastic syndromes (MDS) in adults. Revlimid helps to slow cancer growth, block new blood vessel growth in tumors, and help the immune system fight cancer. Revlimid is available as capsules that are taken once a daily.
Revlimid received FDA approval on December 27, 2005. The active ingredient, sometimes called the generic name, is lenalidomide.
What is Revlimid used for?
Revlimid is used for specific adult patients with:
Multiple Myeloma in combination with dexamethasone. Also, for multiple myeloma maintenance therapy in patients who have had an autologous hematopoietic stem cell transplantation (auto-HSCT).
Myelodysplastic Syndromes with transfusion-dependent anemia due to low- or intermediate-1-risk myelodysplastic syndromes (MDS) associated with a deletion 5q cytogenetic abnormality with or without additional cytogenetic abnormalities.
Mantle Cell Lymphoma (MCL) that has relapsed or progressed after two prior therapies, one of which included bortezomib.
Previously treated Follicular Lymphoma (FL), used in combination with a rituximab product.
Previously treated Marginal Zone Lymphoma (MZL), used in combination with combination with a rituximab product.
Revlimid is not indicated and is not recommended for the treatment of patients with CLL outside of controlled clinical trials.
Revlimid side effects
Common Revlimid side effects may include:
- cold symptoms such as stuffy nose, sneezing, sore throat;
- sleep problems, tiredness;
- weakness;
- headache;
- tremors;
- nosebleed;
- muscle cramps;
- joint pain;
- shortness of breath;
- fever, cough, tiredness;
- itching, rash, swelling; or
- stomach pain, nausea, vomiting, diarrhea, constipation.
Warnings
Never use Revlimid if you are pregnant. Even one dose of lenalidomide can cause severe, life-threatening birth defects or death of a baby if the mother or the father is taking this medicine at the time of conception or during pregnancy.
Use birth control to prevent pregnancy, whether you are a man or a woman.
For women: Use two forms of birth control, beginning 4 weeks before you start taking Revlimid and ending 4 weeks after you stop taking it. See the ‘Before taking this medicine’ section for more information.
For men: Use a condom to prevent pregnancy during your treatment and for up to 4 weeks after your treatment ends. See the ‘Before taking this medicine’ section for more information.
Revlimid may cause blood clots. Stop using this medicine and call your doctor at once if you have symptoms such as sudden numbness, severe headache, problems with vision or speech, chest pain, shortness of breath, coughing up blood, or swelling in your arm or leg.
Revlimid can lower blood cells that help your body fight infections and help your blood to clot. Call your doctor if you have unusual bruising or bleeding or signs of infection (fever, chills, body aches). You will need frequent blood tests while you are taking Revlimid.
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