Buy Dysport Online at The Best Prices in USA | Bioderglow.com
Buy Dysport Online at The Best Prices in USA | Bioderglow.com
Buy Dysport Online at The Best Prices in USA | Bioderglow.com
Buy Dysport Online at The Best Prices in USA | Bioderglow.com

Buy Dysport Online at The Best Prices in USA | Bioderglow.com

Dysport 500 unit

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Dysport has been approved by US FDA in 2009 for carrying out the treatment of cervical dystonia or blepharospasm in the adults, apart from cosmetic treatment.

These have been running successfully over the years.

Each sterile vial contains 500 units of lyophilized abobotulinumtoxinA.

Nonmedicinal ingredients: human serum albumin and lactose.

Botulinum toxin belongs to the class of medications called neuromuscular paralytic agents.

It blocks the nerves that are responsible for muscle activity.

For cosmetic purposes, it can be used to smooth out facial lines and wrinkles, such as those that form between the eyebrows, on the forehead, and around the eyes (crow’s feet).

It gives skin a smoother appearance by relaxing the muscles in the area where it was injected.

It may also be used to treat cervical dystonia, also known as spasmodic torticollis, a condition in which the muscles of the neck stay in a state of contraction, and to treat focal spasticity such as arm spasms after a stroke.

Possible side effects

Drooping of the upper eyelid
Face pain
General feeling of being unwell
Headache
Muscle weakness at the injection site
Nausea
Pain, tenderness or bruising, burning, swelling, or stinging at the injection site
Redness of the skin
Stuffy nose
Tightness of the skin

How to use Dysport 500 unit

Dosage Forms & Strengths

Injection, powder for reconstitution

300 units/vial
500 units/vial

Cervical Dystonia

Indicated for cervical dystonia

Initial: 500 unit IM divided among affected muscles

Retreat every 12-16 weeks or longer: 250-1000 unit IM

Titrate in 250-unit steps

Spasticity

Indicated for treatment of spasticity in adults

Select dose based on muscles affected, severity of muscle activity, prior response to treatment, and adverse event history (EMG guidance recommended)

Do not inject >1 mL at any single injection site; the maximum total dose (upper and lower limb combined) is 1500 units

Repeat treatment when the effect of a previous injection has diminished, but no sooner than 12 weeks after the previous injection

A majority of patients are retreated between 12-16 weeks, although some may have a longer response (eg, 20 wk)

Upper limb spasticity

Dose per muscle
In the clinical trial, doses of 500-1000 units were divided among selected upper limb muscles at a given treatment session
Flexor carpi radialis: 100-200 units in 1-2 sites
Flexor carpi ulnaris: 100-200 units in 1-2 sites
Flexor digitorum profundus: 100-200 units in 1-2 sites
Flexor digitorum sublimis: 100-200 units in 1-2 sites
Brachialis: 200-400 units in 1-2 sites
Brachioradialis: 100-200 units in 1-2 sites
Biceps brachii: 200-400 units divided in 1-2 sites
Pronator Teres: 100-200 units in 1 site
Lower limb spasticity
Dose per muscle
In the clinical trial, doses of 1000-1500 units were divided among selected lower limb muscles at a given treatment session
Gastrocnemius medial head: 100-150 units in 1 site
Gastrocnemius lateral head: 100-150 units in 1 site
Soleus: 330-500 units in 3 sites
Tibialis posterior: 200-300 units in 2 sites
Flexor digitorum longus: 130-200 units in 1-2 sites
Flexor hallucis longus: 70-200 units in 1 site
Glabellar Lines

Indicated for temporary improvement in the appearance of moderate to severe glabellar lines associated with procerus and corrugator muscle activity in adults aged <65 years

50 units total divided in 5 equal doses IM to affected muscles

Retreat no sooner than 3 months

Buy Dysport Online at The Best Prices in USA.

Dosage Modifications

Renal or hepatic impairment: No dose adjustment necessary

Essential Blepharospasm (Orphan)

Orphan indication sponsor

Porton International, Inc; 1155 15th Street, N.W., #315; Washington, DC 20005

Spasmodic Torticollis (Orphan)

Treatment of spasmodic torticollis (cervical dystonia)

Orphan indication sponsor

Ipsen Biopharm Limited; 1 Bath Road Maidenhead, Berkshire, SL6 4UH; UK

Website – https://bioderglow.com/

Buy Dysport Online at The Best Prices in USA | Bioderglow.com

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